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Drug ReportsPixantrone dimaleate
Pixantrone dimaleate
Pixuvri (pixantrone dimaleate) is a small molecule pharmaceutical. Pixantrone dimaleate was first approved as Pixuvri on 2012-05-10. It has been approved in Europe to treat non-hodgkin lymphoma.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
neoplasmsD009369
hemic and lymphatic diseasesD006425
immune system diseasesD007154
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
L: Antineoplastic and immunomodulating agents
— L01: Antineoplastic agents
— L01D: Cytotoxic antibiotics and related substances
— L01DB: Anthracyclines and related substances
— L01DB11: Pixantrone
HCPCS
No data
Clinical
Clinical Trials
18 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-hodgkin lymphomaD008228—C85.9—1———1
LymphomaD008223—C85.9—1———1
Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePixantrone dimaleate
INN—
Description
Pixantrone is a member of isoquinolines.
Classification
Small molecule
Drug classantineoplastics, anthraquinone derivatives
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Structure (InChI/SMILES or Protein Sequence)
NCCNc1ccc(NCCN)c2c1C(=O)c1ccncc1C2=O.O=C(O)/C=C\C(=O)O.O=C(O)/C=C\C(=O)O
Identifiers
PDB—
CAS-ID144510-96-3
RxCUI—
ChEMBL IDCHEMBL2103844
ChEBI ID—
PubChem CID134019
DrugBankDB06193
UNII ID—
Target
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Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 54 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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10 adverse events reported
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